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LEVOFLOXACIN, 5mg/ml, 100ml, bot.

https://unicat.msf.org/cat/product/72639
NST DINJLEFX5B-

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The product is supplied (and stored) sterile, it must remain sterile until its use. Sterile = state of being free from all living microorganisms.
6.2.2 - Watch group antibiotics
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
6.2.5 - Antituberculosis medicines
Classification of the medicines in groups and subgroups according to their therapeutic use. The classification used by MSF is based on the WHO Model List of Essential Medicines.
J01MA12
Anatomical Therapeutic Chemical Classification according to WHOCC
PMFE
The order of this product needs to be justified and is only acceptable under certain conditions.
1525
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OC validations: approved for procurement and use by an OC for international or local orders specifying context and activity in Medical Standard Lists (MSL)
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LEVOFLOXACIN

Therapeutic Action

Anti-infective for systemic use

Fluoroquinolone antibiotic

Indications

Empiric treatment of Gram-negative and Gram-positive infections expected to be susceptible, when oral route is not possible, when other preferred antibiotic options are not possible, such as:

  • community-acquired pneumonia, COPD exacerbation
  • pyelonephritis or complicated urinary tract infections (incl. prostatitis)
  • complicated skin and soft tissue infections
  • intra-abdominal infections
  • diabetic foot infections
  • pelvic inflammatory disease
  • (for some indications, in combination with other antibiotic)

Targeted treatment of severe/critical infections or when oral route is not possible for:

  • second-line treatment (after cotrimoxazole) in infections caused by Burkholderia cepacian, Stenotrophomonas maltophilia.
  • alternative to vancomycin when contraindicated in streptococcal infections.
  • alternative to ciprofloxacin resistant in infections caused by Acinetobacter baumanni (and other Acinetobacter spp).
  • bone and joint infections with susceptible bacteria.
  • plague
  • along with other antibiotics, it may be used in the treatment of tuberculosis.
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Instructions for use

Must be given as slow IV infusion.

Dosage should be determined by susceptibility of the causative organisms, severity and site of infection, and the condition of the patient.

The antibiotic treatment will be started only once culture and antibiotic susceptibility testing (AST) results are available.

Switch to oral levofloxacin as soon as the patient can swallow, until the full course of treatment is completed.

Fluoroquinolones should be used only when preferred options are not possible.

Precautions for Use

Avoid in children, during pregnancy and breast-feeding, unless no alternative.

Storage

  • Below 25ºC - Protect from sunlight
  • Do not refrigerate or freeze.
  • After opening, use the solution immediately.
  • Discard any remaining unused solution.